John Wayne Casserole
Why Make This Recipe?
The John Wayne Casserole is a hearty, layered casserole loaded with bold flavors. With layers of seasoned ground beef, vegetables, and a creamy cheese topping baked to golden perfection, this dish is comfort food at its finest. It’s easy to make, packed with Tex-Mex-inspired flavors, and perfect for feeding a hungry family or entertaining guests.
Recipe Overview
- Servings: 6-8
- Preparation Time: 15 minutes
- Cooking Time: 30 minutes
- Cooling Time: 5 minutes
- Total Time: ~50 minutes
How to Make John Wayne Casserole
Ingredients
- For the Base Layer:
- 1 lb ground beef
- 1 packet taco seasoning (1 oz) ????️
- 1 medium onion, diced ????
- 1 can (10 oz) diced tomatoes with green chilies, drained ????
- 1 can (4 oz) diced green chilies (optional for extra spice)
- For the Biscuit Layer:
- 2 cups Bisquick or similar baking mix
- ½ cup water
- For the Topping:
- 1 cup sour cream ????
- 1 cup mayonnaise
- 2 cups shredded cheddar cheese ????
- ½ cup diced bell peppers (red, green, or a mix) ????️
Directions
- Prepare the Ground Beef Mixture
- In a large skillet over medium heat, cook the ground beef until browned. Drain any excess fat.
- Add the diced onion, taco seasoning, diced tomatoes with green chilies, and green chilies (if using). Stir well and simmer for 5 minutes.
- Make the Biscuit Base
- Preheat your oven to 375°F (190°C).
- In a bowl, mix the Bisquick and water until a dough forms.
- Spread the dough evenly into the bottom of a greased 9×13-inch baking dish.
- Assemble the Casserole
- Spread the ground beef mixture evenly over the biscuit base.
- In a separate bowl, mix the sour cream, mayonnaise, and half of the shredded cheddar cheese. Spread this creamy mixture over the beef layer.
- Top with the remaining cheddar cheese and diced bell peppers.
- Bake
- Bake in the preheated oven for 30 minutes, or until the cheese is melted and bubbly, and the biscuit layer is cooked through.
- Cool and Serve
- Let the casserole cool for 5 minutes before slicing.
How to Serve John Wayne Casserole
Serve this casserole warm with a dollop of sour cream, fresh cilantro, or sliced avocado. Pair it with a side of tortilla chips, a simple green salad, or Mexican rice for a complete meal.
How to Store John Wayne Casserole
- Refrigerate: Store leftovers in an airtight container for up to 3 days.
- Freeze: Freeze the casserole (baked or unbaked) in a freezer-safe dish for up to 2 months. Thaw in the refrigerator overnight before reheating.
- Reheat: Warm in the oven at 350°F (175°C) until heated through or in the microwave for individual portions.
Tips to Make John Wayne Casserole
- Use Freshly Shredded Cheese: Pre-shredded cheese often has anti-caking agents that prevent smooth melting.
- Drain Excess Liquid: Make sure to drain the tomatoes and ground beef to avoid a watery casserole.
- Customize the Heat: Add more green chilies or a dash of hot sauce if you like it spicy.
Variations
- Vegetarian Option: Replace the ground beef with black beans, pinto beans, or a plant-based meat substitute.
- Chicken Twist: Swap the ground beef for shredded rotisserie chicken seasoned with taco spices.
- Breakfast Version: Add scrambled eggs to the beef layer for a hearty breakfast casserole.
Tips for Success
- Even Layers: Spread each layer evenly for balanced flavors in every bite.
- Cook Thoroughly: Ensure the biscuit base is fully cooked by checking the center before serving.
- Prepare Ahead: Assemble the casserole the night before and bake it fresh when ready to serve.
How Many Servings?
This recipe makes 6-8 servings.
Calories and Nutrition Facts (Per Serving)
- Calories: ~450
- Protein: ~20g
- Fats: ~28g
- Saturated Fats: ~10g
- Carbohydrates: ~30g
- Fiber: ~3g
- Sodium: ~800mg
Health Benefits of John Wayne Casserole
- Protein-Packed: Ground beef and cheese provide high-quality protein for muscle repair and energy.
- Rich in Vitamins: Bell peppers and tomatoes add a boost of vitamins A and C for immune support.
- Comfort Food Energy: The biscuit base and creamy layers provide a satisfying, energy-packed meal.
Is It Good for People Over 60 Years Old?
Yes, with minor adjustments:
- Lower Sodium: Use low-sodium taco seasoning and cheese.
- Lightened Creamy Layer: Replace mayonnaise with Greek yogurt for added protein and reduced fat.
- Gentle on Digestion: The soft biscuit base and tender beef make it easy to chew and digest.
FAQs
1. Can I use a different baking mix for the biscuit base?
Yes, any biscuit or pancake mix should work as a substitute for Bisquick.
2. Can I make this casserole spicy?
Absolutely! Add diced jalapeños, hot sauce, or extra chili powder to the beef layer for a spicier dish.
3. Can I freeze individual portions?
Yes, slice the casserole into portions, wrap them in plastic wrap, and freeze for quick, single-serve meals.
John Wayne Casserole is a bold, hearty dish packed with Tex-Mex flavors that’s easy to make and sure to please. Whether for dinner, potlucks, or family gatherings, this casserole is a guaranteed hit. Try it today and see why it’s a favorite!









